Substances
Receptor mechanisms. This hub organizes the topic into a starting point, core reading, and deeper reference material so mobile readers and search systems can understand the page pathway quickly.
Get oriented first
Begin with the plain-language framing before reading narrower claims or legal and safety details.
Read the central articles
Use the core set to understand the topic before moving into edge cases and supporting references.
Education, not instruction
This section does not provide medical, dosing, sourcing, purchasing, or legal advice.
A research-literacy map of the psychedelic substances people microdose or confuse — what each compound is, its class, and what the evidence covers. Education only.
Ketamine, MDMA, and ibogaine are called psychedelics but work through different pathways, so microdosing claims do not transfer. Education only.
Classic Psychedelics Compared: A Description, Not a RankingHow the classic serotonergic psychedelics compare on chemical class, receptor target, duration, and what research covers — described, never ranked or recommended.
LSD and Microdosing: The Ergoline and What Its Research ExaminesLSD as a compound: the ergoline class, its long duration, the self-blinding microdosing studies, and what the evidence does and does not establish. Education only.
Novel psychoactive substances and 'research chemicals' have unknown pharmacology and little safety data — where absence of evidence is not safety. Education only.
Other Classic Psychedelics: DMT, Ayahuasca, Mescaline, and the CactiDMT and ayahuasca, mescaline, peyote and San Pedro: what these classic psychedelics are and why they are largely not microdosed. Research-literacy, education only.
Psilocybin, the Compound: The Molecule Behind the MushroomPsilocybin as a molecule, distinct from the mushroom: a prodrug for psilocin, the most-studied microdosing substance, and what research covers. Education only.
What Microdosing Substance Research Actually CoversThe microdosing evidence base is essentially psilocybin and LSD; for other substances the compound is described far better than any low-dose effect.