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Colorado
Psilocybin legal status, legislation & access — 2025
State-level frameworks do not change federal controlled-substance status.
Status depends on the activity: possession, supervised administration, sale, transport, cultivation, research, and service provision may be treated differently.
What local context does not answer
Local context can explain policy history, state rules, city ordinances, public-health resources, and community support. It cannot determine whether a substance is safe, effective, lawful for a specific person, available through a specific channel, or appropriate for any individual.
Enforcement context
Personal possession under Proposition 122 thresholds carries no criminal penalty as of January 2023. [1]official-stateColorado Proposition 122 — Natural Medicine Health ActLink → Sale without a state licence remains a felony. Federal Schedule I status means federal charges remain possible on federal land — a non-zero risk in Colorado's national park corridors. The Colorado Department of Regulatory Agencies (DORA) is issuing healing centre licences on a rolling basis from 2024 onward.
Cities in Colorado
Local policy context
This section summarizes policy context. It is not legal advice or current-law verification.
Colorado moved on psychedelics from the ground up: a 2019 Denver ballot measure, then a statewide voter initiative in 2022. Reform here has been driven by direct democracy and implemented through state regulators rather than the legislature alone, and it sits inside a state that already normalized voter-led drug policy through cannabis.
Legal and policy timeline
This timeline documents policy and legal history. It does not describe current access options.
- May 2019NewsDenver Initiative 301 passes
Denver becomes the first U.S. city to decriminalize psilocybin mushrooms, making personal-possession enforcement the lowest police priority.source →
- Nov 2022Official (state)Proposition 122 — Natural Medicine Health Act
Voters statewide decriminalize personal possession, cultivation, and sharing of psilocybin and several other natural psychedelics for adults 21+, and authorize a licensed healing-center framework.source →
- 2024NewsHealing-center licensing begins
DORA opens rolling licensure for regulated healing centers, putting Colorado on track to become the second state with supervised psilocybin services.source →
Ballot measure history
Frequently asked questions
Is psilocybin legal in Colorado?
Personal possession of psilocybin mushrooms under Proposition 122 thresholds carries no criminal penalty in Colorado as of January 2023. Sale without a state licence remains a felony. Regulated healing centres are being licensed by DORA from 2024 onward.
What did Colorado Proposition 122 do?
Proposition 122 — the Natural Medicine Health Act — passed in November 2022. It decriminalised personal use and created a licensed healing centre framework for supervised psilocybin therapy, regulated by the Colorado Department of Regulatory Agencies.
Can I visit a psilocybin healing centre in Colorado?
Licensed healing centres began operating in 2024. Adults 21+ may attend supervised sessions at a licensed centre with a trained facilitator. Purchase for personal use outside a licensed centre is not yet legal.
Does this page tell me where to access psilocybin in this state?
No. This page provides legal, policy, and public-health context. It does not list vendors, service centers, providers, sources, shipping options, or access routes.
Is a psilocybin service center the same as a dispensary?
No. Regulated service-center or healing-center models involve supervised administration under program rules. They are not ordinary retail dispensaries, online purchase, shipping, or take-home product systems.
Does state law change federal law?
No. State and federal law are separate systems. State-level programs do not erase federal controlled-substance status; psilocybin remains Schedule I federally.
Are the listed support resources psilocybin providers?
No. They are general mental-health, crisis, veteran, family, disability, or community-support resources. They are not psilocybin providers, access routes, or endorsements.
Mental-health and community-support resources
These are general mental-health, crisis, veteran, disability, family, and community-support resources for anyone in or near Colorado. They are not psilocybin providers, psychedelic services, service centers, vendors, access pathways, or endorsements, and listing them is not a statement that psilocybin or microdosing is safe, legal, or effective as a treatment.
If there is immediate danger, a medical emergency, seizure, chest pain, severe confusion, or risk of self-harm or harm to others, contact emergency services (call 911) or call or text 988 (Suicide & Crisis Lifeline) immediately.
Crisis and mental-health support
Community & peer support
Scope (National / Statewide / Local) indicates a resource's service area, not endorsement by this site.