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New Mexico
Psilocybin legal status, legislation & access — 2025
Legislation
Establishes a state-regulated medical psilocybin program in New Mexico, making it the third U.S. state to authorize medical psilocybin and the first to do so through the legislature rather than a ballot initiative. The Act creates a Medical Psilocybin Advisory Board within the Department of Health, authorizes use in approved clinical settings for qualifying conditions including treatment-resistant depression, PTSD, substance use disorders, and end-of-life care, and establishes a research fund and a treatment equity fund. Program target launch: December 31, 2027.
Enforcement context
New Mexico enacted the Medical Psilocybin Act (SB 219), signed by Governor Michelle Lujan Grisham on April 7, 2025. The law creates a regulated therapeutic access framework under the New Mexico Department of Health. Personal possession of psilocybin outside a licensed facility remains a felony under state law. The DOH is developing licensing regulations with a statutory deadline of December 31, 2027 for full implementation; first licensed patients are targeted by December 2026. Federal Schedule I scheduling means psilocybin remains illegal at the federal level regardless of state law.
Cities in New Mexico
Frequently asked questions
Is psilocybin legal in New Mexico?
Therapeutic psilocybin is legal under the Medical Psilocybin Act (SB 219), signed April 7, 2025. Personal possession outside a licensed facility remains illegal. The NM Department of Health is targeting first licensed patients by December 2026.
When will psilocybin therapy be available in New Mexico?
The New Mexico Department of Health is developing licensing regulations with a statutory deadline of December 31, 2026 for first licensed patients and December 31, 2027 for full programme implementation.
Which New Mexico cities are most likely to have licensed psilocybin facilities?
Albuquerque, as the state's largest city and home to the University of New Mexico, is expected to be the primary licensing market. Santa Fe, as the state capital and location of the NM Department of Health, will also host key regulatory activity.